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RheumatologyReview Article

A study of Na, K - ATPase and arginase activity in peripheral blood lymphocytes in patients with rheumatic diseases

Nataliya Lychkovska, Roman Fafula, Ulyana Efremova, Zinoviy Vorobers
1 April 2025·1 min read·Current Issues in Pharmacy and Medical Sciences

Abstract / Summary

The changes of Na+, K+-ATPase and arginase enzyme activity of peripheral blood lymphocytes in patients with a rheumatoid arthritis and spondyloarthritis have been studied. It was shown the significant decrease of ouabain-sensitive Na+, K+-ATPase enzyme activity in patients with rheumatic diseases in comparison to the practically healthy donors. Also we demonstrated the significant increase of arginase enzyme activity in patients with rheumatic diseases in comparison to the practically healthy donors. The dynamics of Na+, K+-ATPase and arginase enzyme activity changes is observed after patient’s treatment in hospital.

Topics

Na+K+-ATPasearginaserheumatoid arthritisspondyloarthrititslymphocytes

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