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Published by European Association of Urology (EAU) and the European Society for Paediatric Urology (ESPU)
This clinical summary outlines the 2025 EAU/ESPU guideline updates on pediatric urinary tract infections (UTIs). It details diagnostic classifications, urine collection and urinalysis methods, recommendations for renal and bladder ultrasound, targeted antimicrobial selection based on local sensitivity, and various methods for preventing UTI recurrence.
Key Takeaways
The 2025 guidelines update compiles and integrates evidence from a structured literature review covering publications from the previous 2021 update up to February 20, 2024.
Microscopic urinalysis is recommended after a positive dipstick test.
A renal and bladder ultrasound is generally recommended after an initial febrile UTI.
The cornerstone of UTI management is prompt antimicrobial therapy, with the administration route chosen based on several variables.
The antimicrobial agent should be chosen based on local antimicrobial sensitivity patterns, and adjusted according to sensitivity-testing.
Interventions can be considered to prevent UTI recurrence including chemoprophylaxis, non-antibiotic prophylaxis, and treatment of phimosis, bladder-bowel dysfunction and lower urinary tract dysfunction.
Clinical Topic
Urinary tract infection in children
Objectives
To provide a practical approach for both diagnosis and management of urinary tract infections (UTI) and highlight the 2025 update of the EAU/ESPU Guidelines on UTI in children.
Target Patient Population
Children
Diagnostic Criteria
Urinalysis is conducted on urine samples collected via bag, clean catch, catheterization, or suprapubic aspiration using dipstick, microscopy, or flow imaging. Microscopic urinalysis is recommended after a positive dipstick. For further investigation, a renal and bladder ultrasound is recommended after an initial febrile UTI, with additional tests guided by patient and infection characteristics.
Therapeutic Area
UrologyGuideline Scope
Special Populations
Monitoring Guidance
Additional investigations beyond the standard renal and bladder ultrasound should be considered based on the individual patient and infection characteristics.
Difficulty
intermediate
Learning Paths