Prognia
Drug Database
🇪🇺EU · EMAAuthorisedATC: B06AX05Orphan MedicineConditional Approval

Casgevy(Exagamglogene autotemcel)

beta-Thalassemia;Anemia, Sickle Cell

Marketing Authorisation Holder: Vertex Pharmaceuticals (Ireland) Limited

EMA Authorisation: 09/02/2024

INN: exagamglogene autotemcel

Indication

β thalassemia Casgevy is indicated for the treatment of transfusion dependent β thalassemia (TDT) in patients 12 years of age and older for whom haematopoietic stem cell (HSC) transplantation is appropriate and a human leukocyte antigen (HLA) matched related HSC donor is not available. Sickle cell disease Casgevy is indicated for the treatment of severe sickle cell disease (SCD) in patients 12 years of age and older with recurrent vaso occlusive crises (VOCs) for whom haematopoietic stem cell (HSC) transplantation is appropriate and a human leukocyte antigen (HLA) matched related HSC donor is not available.

Official EMA Resources

View on EMA (ema.europa.eu)

AI Drug & Interaction Analysis

Free account required

Ask Prognia AI about Casgevy — dosing recommendations, drug interactions, and current guideline evidence from ESC, EMA, NICE and more.

Medical disclaimer: This information is intended for qualified healthcare professionals. Always verify with the official EMA Summary of Product Characteristics (SmPC) before clinical use.