Every Tool a Modern Clinician Needs.
From AI-powered clinical chat to spaced-repetition flashcards, calculators, and automatic CPD tracking — Prognia brings your entire evidence toolkit into one place.
Start Free — No Credit CardAsk Anything. Get a Cited Answer.
Prognia searches 35M+ PubMed papers, current ESC, AHA, NICE, and ADA guidelines, and a curated clinical case database simultaneously. Every response includes inline citations. Every claim is traceable to a source.
- ESC/AHA/NICE/ADA guidelines indexed within 72h of publication
- Evidence-graded answers (Class I/II, Level A/B/C)
- Cites specific trials — DAPA-HF, EMPEROR-Reduced, PARCOURIR, etc.
- Differential diagnosis, drug interactions, dosing guidance
Per ESC 2023 HF Guidelines, initiate four-pillar therapy simultaneously at low doses:
- 1.ARNI (sacubitril/valsartan) — preferred over ACE-I (Class I, Level B)
- 2.Beta-blocker — bisoprolol, carvedilol, or metoprolol succinate
- 3.MRA — eplerenone preferred over spironolactone with diabetes
- 4.SGLT2-i — dapagliflozin or empagliflozin (dual HF + T2DM benefit)
Know Exactly What Changed.
Compare any two versions of ESC, AHA, NICE, ADA, GOLD, EULAR, or KDIGO guidelines side by side. Upgrades, downgrades, new recommendations, and removed guidance — all highlighted.
- Side-by-side diff view with colour-coded changes
- New recommendations highlighted in green
- Downgraded/removed recommendations in red
- Auto-notified when a guideline you follow is updated
ESC Heart Failure Guidelines
ARNI (sacubitril/valsartan)
Consider as alternative to ACE-I
Class IIaARNI (sacubitril/valsartan)
Preferred over ACE-I for all eligible
SGLT2 inhibitors
Class I, Level A (added in 2021)
Class ISGLT2 inhibitors
Expand to HFmrEF + HFpEF now included
4
Upgrades
6
New recs
1
Removed
Retain What You Learn.
5,000+ clinically focused flashcards across 20 specialties, built around actual exam blueprints (MRCP, USMLE, European boards). A spaced-repetition algorithm schedules your next review at the optimal moment.
- 5,000+ cards covering cardiology, endocrinology, nephrology, and more
- MRCP, USMLE, and European board exam alignment
- SM-2 spaced repetition algorithm
- Create custom decks for your specialty or rotation
Question
When is oral anticoagulation indicated in non-valvular atrial fibrillation?
Tap to reveal answer
Practice That Matches Real Exams.
2,000+ MRCP-style and USMLE-style questions with detailed explained answers that reference the underlying guideline. See which topics you struggle with and improve targeted weak spots.
- 2,000+ MRCP Part 1/2, USMLE Step 2, and board-style questions
- Detailed explanations citing specific guidelines and trials
- Performance analytics by topic and specialty
- Timed and untimed practice modes
A 68-year-old with paroxysmal AF and CHA₂DS₂-VASc score of 3. Which anticoagulant is preferred per ESC 2020 guidelines?
Calculate with Guideline Context.
CHA₂DS₂-VASc, Wells PE, Wells DVT, HAS-BLED, GRACE 2.0, SOFA, Child-Pugh, MELD, and 50+ more. Each calculator shows the recommendation context — not just the score.
- 50+ validated clinical scoring tools
- Each score links to its guideline recommendation
- Interpretive guidance for each risk level
- Works offline on mobile
CHA₂DS₂-VASc Calculator
AF risk scoring3.2–15.2% annual stroke risk
OAC strongly recommended (NOAC preferred).
Log CPD Automatically. Export in One Click.
Every guideline read, flashcard session, quiz attempt, and AI conversation is automatically logged as CPD/CME hours. Export your certificate for GMC, KNMG, BMA, or ABIM revalidation — PDF in one click.
- Auto-logging of all Prognia activity as CPD hours
- Supports GMC, KNMG, BMA, ABIM, and more
- PDF certificate export for regulatory bodies
- Annual progress tracking with visual dashboard
CPD Progress
2024–2025 cycle
12% of annual target
Start Your Clinical AI Journey Today.
Search PubMed, compare guidelines, and track CPD — all in one place. Free forever. No credit card required.